The RFC1 Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to PO-GA, RFC, and RFC1. This antibody recognizes Human, Mouse, and Rat antigen. The RFC1 Antibody has been validated for the following applications: Immunofluorescence, Immunohistochemistry, and Western Blot.
Description
This gene encodes the large subunit of replication factor C, a five subunit DNA polymerase accessory protein, which is a DNA-dependent ATPase required for eukaryotic DNA replication and repair. The large subunit acts as an activator of DNA polymerases, binds to the 3' end of primers, and promotes coordinated synthesis of both strands. It may also have a role in telomere stability. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene